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Table 2 Demographics and characteristics of study participants

From: Genetic polymorphisms of Vascular Endothelial Growth Factor (VEGF) associated with endometriosis in Nigerian women

Characteristics

Control

Case

p-value

Age

32.96 ± 6.91

32.04 ± 7.56

0.527

BMI

24.97 ± 4.71

24.73 ± 4.18

0.790

Parity

0 (0–4)

0 (0–3)

 < 0.0001

Chronic pelvic pain

   

No

42 (84)

15 (30)

 < 0.0001

Yes

8 (16)

35 (70)

 

Painful menstruation

   

No

26 (52)

1 (2)

 < 0.0001

Yes

24 (48)

49 (98)

 

Painful intercourse

   

No

47 (94)

25 (50)

 < 0.0001

Yes

3 (6)

22 (44)

 

I don’t know

3 (6)

 

Bleeding/site of bleeding

   

None

50 (100)

40 (80)

0.001

Umbilicus

10 (20)

 

Blood in stool

   

No

49 (98)

47 (94)

0.702

Yes

3 (6)

 

I don’t know

1 (2)

 

Painful defaecation

   

No

50 (100)

35 (70)

 < 0.0001

Yes

15 (30)

 

Blood in urine

   

No

49 (98)

47 (94)

0.399

Yes

1 (2)

 

I don’t know

1 (2)

2 (4)

 

Painful urination

   

No

50 (100)

36 (72)

 < 0.0001

Yes

14 (28)

 

Convulsion during menstruation

   

No

50 (100)

49 (98)

0.317

I don’t know

1 (2)

 

Coughing up blood

   

No

50 (100)

50 (100)

-

Abdominal swelling

   

No

49 (98)

35 (70)

 < 0.0001

Yes

1 (2)

15 (30)

 

Ascites

   

No

50 (100)

33 (66)

 < 0.0001

Yes

17 (34)

 

Pleural effusion

   

No

50 (100)

43 (86)

0.006

Yes

7 (14)

 

Type of endometriosis

   

Pelvic

50 (100)

27 (54)

 < 0.0001

Extra-pelvic

23 (46)

 

No Symptom

   

NO

31 (62)

50 (100)

 < 0.0001

YES

19 (38)

-

 

Family history of endometriosis

   

No

50 (100)

46 (92)

0.056

Yes

3 (6)

 

I don’t know

1 (2)

 

Method of diagnosis

   

Laparotomy

47 (94)

19 (38)

 < 0.0001

Laparoscopy

3 (6)

15 (30)

 

Clinical features

14 (28)

 

Histology

2 (4)

 

Serum VEGF level (pg/ml)

82.81 [72.90 – 113.82]

82.68 [69.11 – 121.11]

0.967

Serum VEGF level (pg/ml) based on methods of diagnosis

   

Histologically confirmed

Non-histologic diagnosis

82.81 [72.90–113.82]

76.7 [67–123]

82.8 [70.8–113.6]

0.893

  1. Age and BMI are presented as Mean (S.D.), Parity is presented as median (range), Serum VEGF level as Median (IQR), and others as frequency (percentage)