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Table 2 Demographics and characteristics of study participants

From: Genetic polymorphisms of Vascular Endothelial Growth Factor (VEGF) associated with endometriosis in Nigerian women

Characteristics Control Case p-value
Age 32.96 ± 6.91 32.04 ± 7.56 0.527
BMI 24.97 ± 4.71 24.73 ± 4.18 0.790
Parity 0 (0–4) 0 (0–3)  < 0.0001
Chronic pelvic pain    
No 42 (84) 15 (30)  < 0.0001
Yes 8 (16) 35 (70)  
Painful menstruation    
No 26 (52) 1 (2)  < 0.0001
Yes 24 (48) 49 (98)  
Painful intercourse    
No 47 (94) 25 (50)  < 0.0001
Yes 3 (6) 22 (44)  
I don’t know 3 (6)  
Bleeding/site of bleeding    
None 50 (100) 40 (80) 0.001
Umbilicus 10 (20)  
Blood in stool    
No 49 (98) 47 (94) 0.702
Yes 3 (6)  
I don’t know 1 (2)  
Painful defaecation    
No 50 (100) 35 (70)  < 0.0001
Yes 15 (30)  
Blood in urine    
No 49 (98) 47 (94) 0.399
Yes 1 (2)  
I don’t know 1 (2) 2 (4)  
Painful urination    
No 50 (100) 36 (72)  < 0.0001
Yes 14 (28)  
Convulsion during menstruation    
No 50 (100) 49 (98) 0.317
I don’t know 1 (2)  
Coughing up blood    
No 50 (100) 50 (100) -
Abdominal swelling    
No 49 (98) 35 (70)  < 0.0001
Yes 1 (2) 15 (30)  
Ascites    
No 50 (100) 33 (66)  < 0.0001
Yes 17 (34)  
Pleural effusion    
No 50 (100) 43 (86) 0.006
Yes 7 (14)  
Type of endometriosis    
Pelvic 50 (100) 27 (54)  < 0.0001
Extra-pelvic 23 (46)  
No Symptom    
NO 31 (62) 50 (100)  < 0.0001
YES 19 (38) -  
Family history of endometriosis    
No 50 (100) 46 (92) 0.056
Yes 3 (6)  
I don’t know 1 (2)  
Method of diagnosis    
Laparotomy 47 (94) 19 (38)  < 0.0001
Laparoscopy 3 (6) 15 (30)  
Clinical features 14 (28)  
Histology 2 (4)  
Serum VEGF level (pg/ml) 82.81 [72.90 – 113.82] 82.68 [69.11 – 121.11] 0.967
Serum VEGF level (pg/ml) based on methods of diagnosis    
Histologically confirmed
Non-histologic diagnosis
82.81 [72.90–113.82]


76.7 [67–123]
82.8 [70.8–113.6]
0.893
  1. Age and BMI are presented as Mean (S.D.), Parity is presented as median (range), Serum VEGF level as Median (IQR), and others as frequency (percentage)