Table 4 Comparison of VEGF polymorphisms in our study and the published reports
SNP | Population | Cases/controls | MAF [cases/controls] | p-value | References |
|---|---|---|---|---|---|
+ 936 C > T rs3025039 | Chinese | 344/360 | 0.17/0.17 | 0.75 | [13] |
Brazilians | 165/95 | 0.15/0.15 | 0.63 | [14] | |
Iranians | 100/200 | 0.1/0.11 | 0.5 | [24] | |
Japanese | 147/181 | 0.27/0.20 | 0.05 | [25] | |
Tunisians | 105/150 | 0.25/0.13 | 0.001 | [26] | |
This study | 50/50 | 0.05/0.06 | 0.76 | – | |
1000 Genomes phase 3 (MAF): YRI—0.069; CEU—0.152; CHB—0.184; JPT—0.159 (27) | |||||
−460T > C rs833061 | Chinese | 344/360 | 0.23/0.21 | 0.33 | [13] |
Brazilians | 179/107 | 0.43/0.40 | 0.50 | [14] | |
Japanese | 147/181 | 0.28/0.33 | 0.23 | [25] | |
Tunisians | 105/150 | 0.40/0.42 | 0.69 | [26] | |
This study | 50/50 | 0.19/0.26 | 0.24 | - | |
1000 Genomes phase 3 (MAF): YRI—0.296; CEU—0.449; CHB—0.272; JPT—0.337 (27) | |||||
−1154 G > A rs1570360 | Chinese | 344/360 | 0.16/0.22 | 0.004 | [13] |
Brazilians | 267/207 | 0.24/0.16 | 0.01 | [28] | |
This study | 50/50 | 0.09/0.08 | 0.80 | – | |
1000 Genomes phase 3 (MAF): YRI—0.032; CEU—0.283; CHB—0.175; JPT—0.168 (27) | |||||
−2578 C > A rs699947 | Chinese | 344/360 | 0.19/0.26 | 0.002 | [13] |
Iranians | 100/200 | 0.40/0.43 | 0.7 | [24] | |
Brazilians | 218/288 | 0.40/0.32 | 0.03 | [27] | |
This study | 50/50 | 0.14/0.10 | 0.39 | - | |
1000 Genomes phase 3 (MAF): YRI—0.12; CEU—0.455; CHB—0.272; JPT—0.337 (27) |