Fig. 2From: Estimating prevalence of human traits among populations from polygenic risk scoresCorrelation between melanoma and psGRS with regression lines for linear (red), polynomial (blue) and exponential (green) relationships. The data points are colored according to the super populations: AFR (orange), AMR (black), EAS (green), EUR (blue) and SAS (purple). The scale of the x-axis is not the same for both plots due to differing psPRS ranges. A Full model with three regressions: polynomial (r2 = 0.78, p-value: 2.19 × 10−07), exponential (r2 = 0.66, p-value 2.7 × 10−06) and linear (r2 = 0.59; p-value: 1.71 × 10−05). B After maximization: linear regression (r2 = 0.88, p-value: 2.81 × 10−11), polynomial (r2 = 0.94, p-value: 7.36 × 10−13) and exponential (r2 = 0.77, p-value: 3.39 × 10−08). Populations as defined in Fig. 1Back to article page