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Fig. 2 | Human Genomics

Fig. 2

From: Estimating prevalence of human traits among populations from polygenic risk scores

Fig. 2

Correlation between melanoma and psGRS with regression lines for linear (red), polynomial (blue) and exponential (green) relationships. The data points are colored according to the super populations: AFR (orange), AMR (black), EAS (green), EUR (blue) and SAS (purple). The scale of the x-axis is not the same for both plots due to differing psPRS ranges. A Full model with three regressions: polynomial (r2 = 0.78, p-value: 2.19 × 10−07), exponential (r2 = 0.66, p-value 2.7 × 10−06) and linear (r2 = 0.59; p-value: 1.71 × 10−05). B After maximization: linear regression (r2 = 0.88, p-value: 2.81 × 10−11), polynomial (r2 = 0.94, p-value: 7.36 × 10−13) and exponential (r2 = 0.77, p-value: 3.39 × 10−08). Populations as defined in Fig. 1

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