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Fig. 2 | Human Genomics

Fig. 2

From: Cross talk between RNA modification writers and tumor development as a basis for guiding personalized therapy of gastric cancer

Fig. 2

Different expression patterns of RNA modification writers. A Univariate Cox regression of 26 writers and 12 writers had a close relation with GC prognosis. B Spearman rank correlation analysis of 26 writers. Red means positive correlation and blue means negative correlation. C Unsupervised consensus clustering of 300 samples in GSE62254 dataset. Red and violet represent high and low expression, respectively. D Kaplan–Meier survival curve of cluster 1 (165 samples) and cluster 2 (135 samples). Log-rank test was performed. E Enriched KEGG pathways of two clusters analyzed by GSVA. Red and blue represent high and low GSVA enrichment score, respectively. F Enrichment and distribution of 22 immune cells in two clusters. Student t test was performed. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. ns no significance, CI confidence interval, HR hazard ratio

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