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Table 3 Haplotype analysis of the studied polymorphisms of TRIM22 on COVID-19 mortality

From: On the relationship between tripartite motif-containing 22 single-nucleotide polymorphisms and COVID-19 infection severity

rs1063303

rs7935564

rs7113258

Improved patients

Dead patients

OR (95% CI)

P-value

C

A

A

0.4054

0.1434

1.00

–

G

G

T

0.0848

0.3625

6.83 (4.87 –9.58)

 < 0.0001*

G

A

A

0.1843

0.0673

0.93 (0.58 –1.51)

0.78

C

G

A

0.1153

0.0711

1.35 (0.80 –2.29)

0.26

C

G

T

0.0491

0.1269

4.29 (2.59 –7.13)

 < 0.0001*

G

A

T

0.0707

0.0711

3.02 (1.92 –4.76)

 < 0.0001*

G

G

A

0.0386

0.0991

6.34 (3.89 –10.34)

 < 0.0001*

C

A

T

0.0520

0.0587

2.10 (1.16 –3.82)

0.015*

  1. OR odds ratios; CI confidence intervals
  2. *Statistically significant (< 0.05)
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Human Genomics

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