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Fig. 3 | Human Genomics

Fig. 3

From: Genetic etiology and clinical challenges of phenylketonuria

Fig. 3

Protein network interactions contained the PAH and 10 related genes examined in this review created with STRING (https://string-db.org/), where there are strong interactions between the PAH gene and associated BH4 genes. Each node represents all the proteins (n = 11) produced by a single, protein-coding gene locus. Colored nodes describe proteins and the first shell of interactors. Edges represent protein–protein associations (n = 20) that are meant to be specific and meaningful, i.e., proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other

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