Fig. 1From: Noninvasive fetal genotyping of single nucleotide variants and linkage analysis for prenatal diagnosis of monogenic disordersThe rationale of NIFG in fetal genotyping. A The illustration showing how the allelic imbalance between maternal genomic DNA and plasma DNA can be used to infer the genotype of the fetus. B Simulated SPRT and Chi-squared test results when mother is heterozygous and fetus is homozygous for a given SNP locusBack to article page