Fig. 4

Comparison of allele frequencies of pathogenic and likely pathogenic cardiac channelopathy variants across different genomic datasets. The variant allele frequencies in different populations are plotted as solid bubbles (with filled colours). The circles outside the bubbles represent the significantly different allele frequency values (Fisher’s exact test; p < 0.05) using IndiGenomes dataset as a reference. Red asterisk: Fisher’s exact test was not done in case of ESP6500siv2_All dataset due to unavailability of allele numbers and allele counts