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Table 1 Summary of the top six M(H)/L ratio proteins identified by quantitative analysis of the TAP tagging in HEK-293T cells expressing wild-type and mutant ataxin-1

From: Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1

Candidate

Wild-type ataxin-1

Mutant ataxin-1

Accession

Protein

Ratio M/L

Accession

Protein

Ratio H/L

1

P49736

MCM2

4.457

Q5SSJ5

HP1BP3

10.442

2

Q9H813

TMEM206

2.545

P49327

FASN

1.896

3

Q9ULK4

MED23

2.056

P24752

ACAT1

1.771

4

P63092

GNAS

1.758

Q15005

SPCS2

1.498

5

Q9Y5J1

UTP18

1.705

P62491

RAB11A

1.342

6

P49327

FASN

1.607

Q7KZF4

SND1

1.256

  1. The relative abundance ratios (M/L and H/L) > 1.2 were considered candidate ataxin-1-interacting proteins