From: Identification of recurrent variants implicated in disease in bicuspid aortic valve patients through whole-exome sequencing
Gene
Validation cohort
n = 137
Control cohort
n = 130
P value
MIB2
13
0
< 0.001
S100A1
11
1
0.004
TTN
12
3
0.020
CCK
10
2
0.022
NUP205
0.034
LGR4
14
0.003
NCOR2
ESRRB
25
4
WWOX
0.001