Lipid class | Pathway | Lipid | Gene | Direction | p value/fold change |
---|---|---|---|---|---|
Sterol | Steroid biosynthesis | 24,25-Dihydrolanosterol | Â | Decreased | 0.0056 |
Lanosterol |  | Decreased |  < 0.0001 | ||
14-Demethyl-lanosterol | Â | Decreased | 0.0004 | ||
Zymosterol | Â | Decreased | 0.0001 | ||
Zymostenol | Â | Decreased | 0.0106 | ||
Primary bile acid biosynthesis | 25-Hydroxycholesterol |  | Increased |  < 0.0001 | |
7alpha-Hydroxycholesterol | Â | Decreased | 0.0025 | ||
7alpha-hydroxy-4-cholesten-3-one | Â | Decreased | 0.0013 | ||
Free fatty acid | Biosynthesis of unsaturated fatty acids | 20:5 (Eicosapentaenoic acid) |  | Increased |  < 0.0001 |
22:5 (Docosapentaenoic acid) |  | Increased |  < 0.0001 | ||
22:6 (Docosahexaenoic acid) | Â | Increased | 0.0001 | ||
20:3 N9 (Eicosatrienoic acid) | Â | Decreased | 0.0037 | ||
20:4 (Arachidonic acid) |  | Increased |  < 0.0001 | ||
22:4 (Adrenic acid) |  | Increased |  < 0.0001 | ||
20:1 (Icosenoic acid) | Â | Decreased | 0.0199 | ||
Linoleic acid metabolism | 20:4 (Arachidonic acid) |  | Increased |  < 0.0001 | |
20:3 N9 (Eicosatrienoic acid) | Â | Decreased | 0.0037 | ||
 | PLA2G4A | Decreased | – 8.14 | ||
Phospholipid | Glycerophospholipid metabolism | Phosphatidylglycerol | Â | Increased | 0.0189 |
Phosphatidylserine | Â | Increased | 0.0072 | ||
 | PLA2G4A | Decreased | – 8.14 | ||
 | GPAT4 | Decreased | –10.64 | ||
Acylcarnitine | Fatty acid degradation | CAR 16:0 (L-palmitoylcarnitine) | Â | Increased | 0.0004 |