Skip to main content

Table 2 Results of coagulative analysis in the studied family

From: Immune dysregulation associated with co-occurring germline CBL and SH2B3 variants

Patient

vWF reduction

LAC

INR (n.v. 0.9–1.2)

aPTT (n.v. 0.85 – 1.25)

Coagulation factors

III.1

 

Normal

Normal

n.d

III.2

 + 

1.22

1.50 (1.11 after correction with normal plasma)

Slight reduction in II, V, X, XI, XII

III.3 pre HSCT

 + 

1.54

1.48

n.d

III.3 post-HSCT

1.1

0.96

n.d

II.1

n.d

n.d

n.d

II.2

 + 

n.d

n.d

n.d

II.3

 + 

 + 

n.d

n.d

Slight reduction in fXI

I.1

 + 

 + 

n.d

n.d

n.d

I.2

n.d

n.d

n.d

I.3

 + 

 + 

n.d

n.d

n.d

  1. III.2, III.2, II.3, I.1 and I.3 show a vWF reduction. Coagulation factors consumption was observed in III.2