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Fig. 2 | Human Genomics

Fig. 2

From: CRISPR-Cas9-mediated functional dissection of the foxc1 genomic region in zebrafish identifies critical conserved cis-regulatory elements

Fig. 2

Changes in gene expression in mutants carrying deletions of upstream regions. AF qRT-PCR relative expression of foxc1a (A) and foxc1b (B), foxf2a (C) and foxq1a (D) and foxf2b (E) and foxq1b (F) in 1-, 2-, 3- and 4-dpf wild-type, foxc1a∆CEU1a and/or foxc1b∆CEU1b homozygous zebrafish embryos (whole bodies). G, H qRT-PCR relative expression of foxc1a (G) and foxc1b (H) in 1-, 2-, 3- and 4-dpf wild-type, foxc1a∆UPa and foxc1b∆UPb homozygous embryos. β-actin (actb1) was used as the reference transcript in all experiments. *: p < 0.05; **: p < 0.01; ***: p < 0.001; ****: p < 0.0001

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