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Table 2 Association of mutations in selective pathways with clinical phenotypes

From: De novo mutations within metabolism networks of amino acid/protein/energy in Chinese autistic children with intellectual disability

Phenotypes

Protein synthesis

Pressure

Energy metabolism

Development

AA metabolism

Related

Unrelated

Related

Unrelated

Related

Unrelated

Related

Unrelated

Related

Unrelated

Total genes

47

24

23

48

15

56

37

34

12

59

IQ/DQ

 < 60

16

17

7

26

2

31

18

15

2

31

 ≥ 60

22

6

11

17

10

18

15

13

8

20

P

0.019

 

0.162

 

0.008

 

1.00

 

0.034

 

OR

0.26

 

0.42

 

0.12

 

1.04

 

0.17

 
  1. IQ intelligence quotient. DQ developmental quotient