Fig. 4
From: Mutation in XPO5 causes adult-onset autosomal dominant familial focal segmental glomerulosclerosis
In silico analysis of the identified XPO5 missense variant. A Evolutionary conservation analysis of identified XPO5 variant; B the predicted structure of wild-type (Valine) residue of XPO5; C the predicted structure of mutant residue (p.V552A). The mutant XPO5 (V552A) effect on hydrogen bonding in protein structure. Red residue are sites of variant and wild type, while interacting hydrogen-bonded residues are shown in blue. The yellow dotted lines are displaying hydrogen bonding