Skip to main content

Table 2 IFITM3 rs6598045 association with COVID-19 mortality

From: Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant

Model

Genotype

Groups

OR (95% CI)

P-value

AIC

BIC

Recovered patients (%)

Deceased patients (%)

Allele

A

2124 (79.0)

888 (39.0)

 

G

560 (21.0)

1410 (61.0)

Codominant

A/A

897 (66.8)

190 (16.5)

1.00

 < 0.0001*

2710.2

2733.5

 

A/G

330 (24.6)

508 (44.2)

7.27 (5.90–8.96)

   
 

G/G

115 (8.6)

451 (39.2)

18.51 (14.31–23.96)

   

Dominant

A/A

897 (66.8)

190 (16.5)

1.00

 < 0.0001*

2766.9

2784.4

 

A/G-G/G

445 (33.2)

959 (83.5)

10.17 (8.39–12.34)

   

Recessive

A/A-A/G

1227 (91.4)

698 (60.8)

1.00

 < 0.0001*

3098.5

3115.9

 

G/G

115 (8.6)

451 (39.2)

6.89 (5.51–8.63)

   

Overdominant

A/A-G/G

1012 (75.4)

641 (55.8)

1.00

 < 0.0001*

3336.8

3354.3

 

A/G

330 (24.6)

508 (44.2)

2.43 (2.05–2.88)

   
 

Recovered patients

 Deceased patients

 All patients

   

Minor allele frequency (G)

0.21

0.61

0.41

 –

 –

  1. IFITM3: Interferon-induced Transmembrane Protein 3; COVID-19: Coronavirus disease 2019; OR: Odds ratios; CI: confidence intervals; AIC: Akaike information criterion; BIC: Bayesian information criterion
  2. *Statistically significant (< 0.05)