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Table 2 Enrichment analysis of rare variants in TP73 in amyotrophic lateral sclerosis

From: Lack of association of TP73 rare variants with amyotrophic lateral sclerosis in a Chinese cohort

Variant group

MAF < 0.01

MAF < 0.001

Case

Control

P

Case

Control

P

All variants

34

45

0.47

28

34

0.49

Damaging variants

11

20

0.71

10

9

0.32

  1. Rare variant denotes variants with minor allele frequency < 0.01; Ultra-rare variant denotes variants with minor allele frequency < 0.001. Damaging variants denote variants which were predicted as damaging by REVEL (score > 0.7). Case and Control denotes the number of alleles detected in patients and controls