Table 5 Predictors of discovering at least one variant classified as likely pathogenic or pathogenic in univariate and multivariable analyses

Suspected diagnosis subgroup, Lysosomal disorder

2.15

(1.1)

8.55

(0.99–73.84)

2.01 × 10⁻²

2.47

(1.11)

11.81

(1.35–103.33)

Suspected diagnosis subgroup, Hypercholesterolemia

1.28

(0.33)

3.61

(1.9–6.86)

5.62 × 10⁻⁵

1.42

(0.33)

4.14

(2.15–7.96)

Pediatric care department

0.55

(0.21)

1.73

(1.15–2.6)

8.29 × 10⁻³

0.67

(0.22)

1.96

(1.28–2.99)

Suspected diagnosis subgroup, cholestatic disorder

 − 1.93

(1.05)

0.15

(0.02–1.14)

1.84 × 10⁻²

Not retained§

Suspected diagnosis group, Dyslipidemia

0.56

(0.26)

1.75

(1.06–2.89)

2.89 × 10⁻²

Not used in the model||

Adult care department

 − 0.55

(0.21)

0.58

(0.38–0.87)

8.29 × 10⁻³

Not used in the model||