Genetic basis of STEM occupational choice and regional economic performance: a UK biobank genome-wide association study

Table 2 Summary of top loci for STEM trait identified from GWAS

SNP	CHR	BP	A1	A2	EAF	Beta	SE	P	Nearest Gene(s)	Function
rs10048736	2	144,239,303	A	G	0.36	0.086	0.014	1.46E−09	*ARHGAP15*	Intron Variant
rs12691680	2	144,204,338	T	C	0.36	0.086	0.014	1.94E−09	ARHGAP15	Intron Variant
rs12903858	15	45,972,166	C	T	0.43	− 0.086	0.014	2.26E−09	*SQOR/SQRDL*	Intron Variant
rs770075436	2	144,228,576	T	TAAAG	0.35	0.085	0.014	2.45E−09	ARHGAP15	Intron Variant
rs13411140	2	144,215,811	T	C	0.36	0.085	0.014	2.74E−09	ARHGAP15	Intron Variant
rs28684621	2	144,231,584	G	T	0.36	0.084	0.014	3.77E−09	ARHGAP15	Intron Variant
rs56081031	2	144,197,423	C	A	0.27	− 0.092	0.016	4.56E−09	ARHGAP15	Intron Variant
rs28380327	2	144,232,491	T	A	0.36	0.084	0.014	4.59E−09	ARHGAP15	Intron Variant
rs35789697	2	144,248,718	A	G	0.35	0.084	0.014	4.89E−09	ARHGAP15	Intron Variant
rs2381455	2	144,182,917	G	T	0.27	− 0.089	0.016	1.73E−08	ARHGAP15	Intron Variant
rs6705184	2	144,265,362	G	C	0.5	0.079	0.014	1.96E−08	ARHGAP15	Intron Variant
rs4662334	2	144,241,887	G	A	0.36	0.08	0.014	2.20E−08	ARHGAP15	Intron Variant
rs12617059	2	144,238,363	T	G	0.27	− 0.087	0.016	2.91E−08	ARHGAP15	Intron Variant
rs12999615	2	144,149,614	A	T	0.27	− 0.087	0.016	3.08E−08	ARHGAP15	Intron Variant
rs4402695	2	144,259,542	T	C	0.27	− 0.087	0.016	3.94E−08	ARHGAP15	Intron Variant
rs57014442	2	144,220,812	AAT	A	0.27	− 0.086	0.016	4.04E−08	ARHGAP15	Intron Variant
rs35564832	2	144,237,261	G	A	0.27	− 0.086	0.016	4.14E−08	ARHGAP15	Intron Variant
rs13020925	2	144,263,416	C	T	0.27	− 0.087	0.016	4.52E−08	ARHGAP15	Intron Variant

The bold SNPs are independent genetic loci associated with participants’ choice of STEM jobs

ISSN: 1479-7364