https://humgenomics.biomedcentral.com/articles/10.1186/s40246-016-0095-x https://humgenomics.biomedcentral.com/articles/10.1186/s40246-016-0093-z https://humgenomics.biomedcentral.com/articles/10.1186/s40246-016-0094-y https://humgenomics.biomedcentral.com/articles/10.1186/s40246-016-0092-0