Figure 1

Schematic diagram of KLHL family members drawn to scale with amino acid numbers listed on the right. ‘BTB,’ ‘BACK,’ and ‘K’ indicate the BTB domain, BACK domain, and Kelch domains, respectively. In case of multiple isoforms, only the first one is depicted. Data was collected from [20] using a motif scan with Pfam HMMs (global or local models).