Table 1 qPCR and WGSA results on c-MYC and p16 genes
From: Whole genome DNA copy number changes identified by high density oligonucleotide arrays
c-Mycregion on chromosome 8 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Marker/sample | SNP 55150 (300 kb distal) | SNP 511315 (196 kb distal) | |||||||
|  |  | 12ΔCt+1 | 2WGSA | 3Sig |  | 2ΔCt+1 | WGSA | Sig | |
Sk-BR-3 | Â | 32.00 | 15.87 | < - 20 | Â | 22.63 | 21.12 | - 11.89 | |
MCF-7 | Â | 9.19 | 4.54 | - 3.47 | Â | 7.46 | 6.25 | - 1.89 | |
ZR-75-30 | Â | 13.00 | 7.64 | -7.67 | Â | 11.31 | 16.31 | -9.95 | |
Hs578 Bst | Â | 2.60 | 2.54 | -0.86 | Â | 2.64 | 3.21 | -0.77 | |
p 16 region on chromosome 9 | |||||||||
Marker/sample | SNP 827951 (235 kb proximal) | SNP 139369 (inside p 16) | SNP 87445 (21 kb distal) | ||||||
|  | 2 ΔCt+1 | WGSA | Sig | 2 ΔCt+1 | WGSA | Sig | 2 ΔCt+1 | WGSA | Sig |
BT-20 | 1.82 | 1.92 | -0.31 | 0.008 | 0.23 | -12.06 | 1.32 | 1.57 | -0.71 |
MCF-12A | 1.29 | 1.02 | -1.46 | 0.014 | 0.27 | -10.44 | 0.08 | 0.57 | -8.12 |
MCF-7 | 1.33 | 1.82 | -0.37 | 0.002 | 0.25 | -10.83 | 1.00 | 0.95 | -2.68 |
Hs578 Bst | 2.28 | 1.87 | -0.35 | 1.073 | 1.61 | -0.60 | 1.23 | 1.75 | -0.56 |