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Featured article: Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens

New Content Item​​​​​​​Despite a number of different transgenes that can mediate DNA deletion in the developing lens, each has unique features that can make a given transgenic line more or less appropriate for particular studies. In their work, Lam et al. provide a review of transgenes that lead to the expression of Cre recombinase in the lens and a comparative analysis of currently available transgenic lines that can mediate DNA deletion in the lens placode.  They suggest that abnormal eye development in Le-Cre transgenic mice stems from CRE toxicity

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HGNC updates

Updates from the HUGO Gene Nomenclature Committee (HGNC) relevant to Human Genomics readers.

Previous content

Human Genomics launched with BioMed Central in July 2012, transferring from its previous publisher Henry Stewart Publications. All back content is now available in the archive.

Aims and scope

Human Genomics is a peer-reviewed, open access journal that focuses on the application of genomic analysis in all aspects of human health and disease, as well as genomic analysis of drug efficacy and safety, and comparative genomics.

Call for Papers: Public Health Genomics

Guest Editors: George P Patrinos, University of Patras, Greece; Hongyu Zhao, Yale University, USA

Papers are invited which address current issues in human public health genomics, such as genomic surveillance of disease, genetic risk prediction, individual genome interpretation, gene-environment interactions, genetic diversity of vector-borne disease, vaccination and vaccine-based approaches against pathogens data sharing, economic evaluation in genomic medicine, and the role of big data and artificial intelligence on the development of translational tools and services and the overall future of public health.

Submission Deadline: March 2020

HUGO 2019 Meeting: April 24-26 in Seoul, South Korea

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This year's theme is "Towards Implementing Genomic Medicine". Read more here

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