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Table 1 List of xenobiotic metabolising enzyme

From: Cytochrome P450 humanised mice

Enzymes

Reference

Phase 1

 

Cytochrome P450s (P450 or CYP)

http://drnelson.utmem.edu/CytochromeP450.html

Flavin-containing monooxygenases (FMO)

1

Epoxide hydrolases (mEH, sEH)

2

Phase 2 'transferases'

 

Sulfotransferases (SULT)

3

UDP-glucuronosyltransferases (UGT)

4

Glutathione S-transferases (GST)

5

NAD(P)H-quinone oxidoreductase (NQO)

6

N-acetyltransferases (NAT)

7

  1. mEH and sEH are microsomal and soluble epoxide hydrolase.
  2. Abbreviations: UDP uridine diphosphate; NAD(P) reduced nicotinamide adenine dinucleotide (phosphate).