Figure 2
From: How homologous recombination generates a mutable genome
Simplified view of the outcomes of homologous recombination (HR). HR is initiated by a double-strand break and, after several processing steps, an intermediate, known as a Holliday junction, is formed, in which two homologous sequences are conjoined. This intermediate can then be resolved in one of two ways, resulting in a crossover or a gene conversion event. Current models of HR posit two Holliday junctions within a more complex intermediate structure;[32] however, the details of these models are beyond the scope of this paper.