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Table 1 Genes responsible for inherited deafness (DFN) with neighbouring microsatellite markers used in the subgenome scan.

From: Genomic analysis of a heterogeneous Mendelian phenotype: multiple novel alleles for inherited hearing loss in the Palestinian population

Chromosome Distance from pter (MB) Gene DFN locus Size of gene (kb) Flanking markers and kb spanned
1 p36.31 6.4 ESPN B36 36 D1S253 D1S2731 342
1 p34.3 34.9 GJB3 A2 5 D 1S1570 D1S496 190
1 p34.2 40.9 KCNQ4 A2 55 D1S2706 D1S1188 273
2 p23.3 26.6 OTOF B9 102 D2S2350 D2S174 112
3 p21.31 46.7 TMIE B6 9 AC(46.635) TG(46.779) 144
4 p16.1 6.4 WFS1 A6/A14 33 TCCC(6.457) D4S431 77
5 q31.3 140.9 DIAPH1 A1 104 D5S2119 D5S2010 254
5 q32 145.7 POU4F3 A15 1 D 5S2099 D5S2033 628
6 p21.32 33.2 COL11A2 A13 30 D6S2414 D6S1701 449
6 q14.1 76.6 MY O6 B37/A22 167 AC (76.528) GT(76.674) 146
6 q23.2 133.7 EYA4 A10 288 D6S975 D6S1722 517
7 p15.3 24.5 DFN A5 A5 51 D7S2444 D7S2493 477
7 q22.1 102.6 SLC26A5 (Prestin) B61 93 D7S2509 D7S2504 478
7 q31.1 106.9 SLC26A4 (Pendrin) B4 57 D7S496 D7S2459 177
8 q22.3 102.6 TFCP2L3 A28 177 D8S521 D8S1046 761
9 q21.13 72.4 TMC1 B7/B11/A36 315 D9S1837 D9S1876 48
9 q32 114.3 WHRN B31 103 D9S1824 D9S1855 619
10 p12.1 26.4 MY03A B30 278 D10S2481 D10S1775 60
10 q21.1 56.0 PCDH15 B23 980 D10S546 D10S1642 321
10 q22.1 73.0 CDH23 B12 420 D10S584 D10S1694 152
11 p15.1 17.5 USH1C (Harmonin) B18 51 D11S902 D11S4138 268
11 q13.5 76.6 MY07A B2/A11 87 D11S4179 D11S4186 573
11 q23.3 120.5 TECTA B21/A8/A12 88 D11S4089 D11S4107 60
12 q13.3 55.7 MY O1A A48 22 D12S1644 D12S1691 1
13 q12.11 19.7 GJB2 (Connexin26) B1/A3 5 D 13S1316 D13S175 167
13 q12.11 19.7 GJB6 (Connexin31) B1/A3 9 D 13S1316 D13S175 167
14 q12 30.4 COCH A9 16 D14S1021 D14S54 256
15 q15.3 41.7 STRC B16 19 TG(41.690) TG(41.707) 17
16 p12.2 21.2 CRYM A40 20 D16S3045 TTA(21.603) 661
16 p12.2 21.6 OTOA B22 82 D16S3045 TTA(21.603) 661
17 p11.2 18.0 MY015A B3 71 AC (17.958) AA T(18.013) 55
17 q25.3 77.1 ACTG1 A20/A26 3 G T(77.007) CA (77.107) 100
19 q13.33 55.4 MYH14 A4 107 D19S866 D19S904 22
21 q22.13 36.8 CLDN14 B29 20 D21S1252 D21S167 369
21 q22.3 42.7 TMPRSS3 B8/B10 25 D21S1225 GT(43.277) 740
22 q12.3 35.1 MYH9 A1720 107 D22S1173 D22S283 115
22 q13.1 36.4 TRIOBP B28 89 TG(36.464) CA (36.494) 30
  1. DFNA loci are DFN loci associated with dominant (A) hearing loss; DFNB loci are DFN loci associated with recessive (B) hearing loss.