Figure 2

Phylogenetic organisation of selected NQO genes in bacteria and eukaryotes. Metma, Methanosarcina mazei (an archaebacterium); Cavpo, Cavia porcellus (guinea pig); Musmu, Mus musculus; Ratno, Rattus norvegicus; Bosta, Bos taurus; Canfa, Canis familiaris; Macfa, Macaca fascicularis (macaque); Ponpy, Pongo pygmaeus (orangutan); Homsa, Homo sapiens; Pantr, Pan troglodytes (chimpanzee); Xentr, Xenopus tropicalis; Danre, Danio rerio (zebrafish); Oryla, Oryzias latipes (ray-finned fish); Galga, Gallus gallus (chicken); Tetni, Tetraodon nigroviridis (puffer fish); Pseae, Pseudomonas aeruginosa; Psepu, Pseudomonas putida; Rossp, Roseovarius_sp_217; Rhopa, Rhodopseudomonas palustri; BurcePC184, Burkholderia cenocepacia PC184; BurceAU1054, Burkholderia Burkholderia cenocepacia AU 1054; Frasp, Frankia sp; Cangl, Candida glabrata; Trimo, Triticum monococcum; Orysa, Oryza sativa (rice); Trive, Triphysaria versicolor; Arath, Arabidopsis thaliana; QR2, quinone reductase-2, which belongs to the flavodoxin-1 fold, and not to the flavodoxin-2 (NQO) fold. No NQO genes were found in Caenorhabditis elegans, Drosophila melanogaster or Ciona savignyi (sea squirt), nor in several plants whose genomic databases were searched.