Figure 4
From: Whole-genome approach implicates CD44in cellular resistance to carboplatin
Baseline expression correlation of CD44 with carboplatin IC 50 . (a) Linear regression of log2 transformed carboplatin IC50 values on log2 transformed baseline CD44 expression (from exon expression array) and in 57 unrelated HapMap cell lines. (b) Quantitative real-time polymerase chain reaction analysis of normalised CD44 expression in lymphoblastoid cell lines with the highest (resistant, n = 8) and lowest (sensitive, n = 10) carboplatin IC50 values. Each box represents biological triplicates run in duplicate (*p < 0.01, Student's t-test).