Table 2 Biological processes and molecular functions enriched in the 3,734 genes forming TT pairs closer than 10 kb, a size range significantly enriched in TT gene pairs
From: Orientation, distance, regulation and function of neighbouring genes
Biological process | Observed | Expected | pValue |
|---|---|---|---|
Protein modification | 236 | 167.74 | 2.87 × 10-5 |
Protein metabolism and modification | 536 | 440.74 | 4.44 × 10-5 |
Chromatin packaging and remodelling | 64 | 34.36 | 5.13 × 10-4 |
Cell structure and motility | 221 | 166.44 | 6.28 × 10-4 |
DNA repair | 48 | 24.5 | 3.19 × 10-3 |
Nucleoside, nucleotide and nucleic acid metabolism | 561 | 484.67 | 4.48 × 10-3 |
Intracellular protein traffic | 189 | 146.14 | 9.02 × 10-3 |
Protein phosphorylation | 134 | 95.69 | 2.01 × 10-2 |
Molecular function | Observed | Expected | p Value |
Select regulatory molecule | 248 | 172.53 | 5.07 × 10-7 |
Hydrolase | 166 | 106.71 | 1.16 × 10-6 |
Kinase | 155 | 99.17 | 2.46 × 10-6 |
Transferase | 180 | 128.16 | 1.78 × 10-4 |
Nucleic acid binding | 491 | 413.19 | 1.18 × 10-3 |
Other enzyme regulator | 27 | 10.44 | 2.10 × 10-3 |
Transporter | 129 | 93.95 | 8.47 × 10-3 |
Protein kinase | 112 | 76.69 | 1.25 × 10-2 |
Histone | 28 | 12.47 | 1.63 × 10-2 |
Non-receptor serine/threonine protein kinase | 71 | 43.93 | 1.91 × 10-2 |