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Table 3 Frequencies of the eNOS 894G > T genotypes and alleles in CABG patients according to their smoking behaviour

From: Endothelial nitric oxide synthase gene polymorphisms -786T >C and 894G >Tin coronary artery bypass graft surgery patients

 

CABG current/past smokers

(n= 72)

CABG never smokers

(n= 82)

eNOS 894G > T genotypes

n (%)

95% CI

n (%)

95% CI

GG

27 (37.5)

26.9-49.0

47 (57.3)

46.5-67.6

GT

33 (45.8)

34.7-57.3

30 (36.6)

26.8-47.3

TT

12 (16.7)

9.5-26.5

5 (6.1)

2.4-12.9

p value

 

0.02* / 0.01**

 

Alleles

n = 144

n = 164

G

87 (60.4)

52.3-68.1

124 (75.6)

68.6-81.7

T

57 (39.6)

31.9-47.7

40 (24.4)

18.3-31.4

p value

  

<0.01

 
  1. *p value = 0.02 for comparison among all eNOS 894G > T genotypes in current/past smoker and never smoker CABG patients.
  2. **p value = 0.01 for comparison between eNOS 894GG and TT genotypes in current/past smoker and never smoker CABG patients.
  3. Genotype and allele frequencies between the two groups were analysed using the chi-square test.
  4. Abbreviations: CABG, coronary artery bypass graft; CI, confidence interval.
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Human Genomics

ISSN: 1479-7364