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Table 2 Amino acid sequence identity between type I and type II human acyl-CoA thioesterases (ACOTs).

From: Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family

Type I ACOTs

        
 

ACOT1

ACOT2

ACOT4

ACOT6

BAAT

   

ACOT1

        

ACOT2

98%

       

ACOT4

70%

70%

      

ACOT6

57%

57%

54%

     

BAAT

45%

45%

45%

37%

    

Type II ACOTs

        
 

ACOT7

ACOT8

ACOT9

ACOT11

ACOT12

ACOT13

THEM4

THEM5

ACOT7

        

ACOT8

--

       

ACOT9

19%

--

      

ACOT11

22%

--

--

     

ACOT12

24%

--

22%

51%

    

ACOT13

--

--

--

--

--

   

THEM4

--

--

--

--

--

22%

  

THEM5

--

--

--

--

--

--

37%

 
  1. Identity was determined using BLASTP and non-redundant human protein sequences. The predominant isoform sequences were used for ACOTs having multiple protein variants. Homology was considered not significant and left blank if the observed identity was less than 15 per cent
  2. Abbreviations: BAAT, bile acid CoA:amino acid N-acyltransferase; THEM, thioesterase superfamily member