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Table 1 Human IL and IL-related cytokines.

From: Evolutionary divergence and functions of the human interleukin (IL) gene family

Gene Full gene name Aliases Human
    Chromosome Isoforms Ref seq mRNA number Ref seq protein number AA#
IL1A Interleukin 1, alpha IL1F1, IL1A,
IL-1A, IL1,
IL1-ALPHA
2q14   NM_000575.3 NP_000566.3 270
IL1B Interleukin 1, beta IL1F2, IL1B, IL-1,
IL1-BETA
2q14   NM_000576.2 NP_000567.1 268
IL1RN Interleukin 1 receptor antagonist DIRA, IRAP ,
IL1F3, IL1RA,
MVCD4,
IL1RN, IL1ra,
IL1ra3,
ICIL1RA,
MGC10430,
ICIL-1RA,
IL-1RN
2q14.2   NM_173842.2 NP_776214.1 177
IL1F5 Interleukin 1 family, member 5 UNQ1896/PRO4342, FIL1,
FIL1(DELTA), FIL1D,
IL1HY1, IL1L1,
IL1RP3,
MGC29840
2q14   NM_173170.1 NP_775262.1 154
IL1F6 Interleukin 1 family, member 6 FIL1,
FIL1(EPSILON),
FIL1E,
IL-1F6,
IL1(EPSILON),
MGC129552,
MGC129553
2q12-q14.1   NM_014440.1 NP_055255.1 157
IL1F7 Interleukin 1 family, member 7 FIL1, FIL1(ZETA),
FIL1Z, IL-1F7,
IL-1H4,
IL-1RP1, IL1H4,
IL1RP1
2q12-q14. 1 Isoform 1 NM_014439.3 NP_055254.2 217
     Isoform 2 NM_173202.1 NP_775294.1 197
     Isoform 3 NM_173203.1 NP_775295.1 157
     Isoform 4 NM_173204.1 NP_775296.1 178
     Isoform 5 NM_173205.1 NP_775297.1 192
IL1F8 Interleukin 1 family, member 8 FIL1, FIL1-(ETA),
FIL1H, IL-1F8,
IL-1H2, IL1-ETA,
IL1H2,
MGC126880,
MGC126882
2q14   NM_014438.3 NP_055253.2 163
IL1F9 Interleukin 1 family, member 9 UNQ2456/PRO5737,
IL-1F9, IL-1H1,
IL-1RP2,
IL1E, IL1H1,
IL1RP2
2q12-q21   NM_019618.2 NP_062564.1 168
IL1F10 Interleukin 1 family, member 10 FKSG75,
FIL1-theta,
IL-1HY2,
IL1-theta,
MGC119831,
MGC119832,
MGC119833
2q13   NM_032556.4 NP_115945.4 151
IL2 Interleukin 2 IL-2, TCGF ,
lymphokine
4q26-q27   NM_000586.3 NP_000577.2 152
IL3 Interleukin 3 IL-3, MCGF ,
MGC79398,
MGC79399,
MULTI-CSF
5q23-q31   NM_000588.3 NP_000579.2 151
IL4 Interleukin 4 BCGF-1, BCGF1,
BSF1, IL-4,
MGC79402
5q23-q31 Isoform 1 NM_000589.2 NP_000580.1 152
     Isoform 2 NM_172348.1 NP_758858.1 137
     Isoform 2 NM_172348.1 NP_758858.1 137
IL5 Interleukin 5 EDF, IL-5, TRF 5q23-q31   NM_000879.2 NP_000870.1 133
IL6 Interleukin 6 BSF2, HGF, HSF ,
IFNB2, IL-6
7p21   NM_000600.3 NP_000591.1 211
IL7 Interleukin 7 IL-7 8q12-q13   NM_000880.2 NP_000871.1 176
IL8 Interleukin 8 CXCL8, GCP-1,
GCP1, LECT, LUCT ,
LYNAP, MDNCF ,
MONAP, NAF ,
NAP-1, NAP1
4q13-q21   NM_000584.2 NP_000575.1 98
IL9 Interleukin 9 HP40, IL-9, P40 5q31-q35   NM_000590.1 NP_000581.1 143
IL10 Interleukin 10 RP11-262N9.1,
CSIF, IL-10,
IL10A,
MGC126450,
MGC126451,
TGIF
1q31-q32   NM_000572.2 NP_000563.1 177
IL11 Interleukin 11 AGIF, IL-11 19q13.3-q13.4   NM_000641.2 NP_000632.1 198
IL12A Interleukin 12A CLMF, IL-12A,
NFSK, NKSF1, P35
3q25.33-q26   NM_000882.2 NP_000873.2 252
IL13 Interleukin 13 ALRH, BHR1,
IL-13,
MGC116786,
MGC116788,
MGC116789,
P600
5q31   NM_002188.2 NP_002179.2 145
TXLNA Taxilin alpha IL14,
DKFZp451J0118,
MGC118870,
MGC118871,
RP4-622L5.4,
TXLN
1p35.1   NM_175852.3 NP_787048.1 546
IL15 Interleukin 15 IL-15, MGC9721 4q31   NM_001044731.1 NP_000576.1 161
IL16 Interleukin 16 FLJ16806,
FLJ42735,
FLJ44234, LCF ,
NIL16, PRIL16,
prIL-16
15q26.3 Isoform 1 NM_004513.5 NP_004504.3 631
     Isoform 2 NM_172217.3 NP_757366.2 1332
     Isoform 3 NM_001172128.1 NP_001165599.1 1331
IL17A Interleukin 17A CTLA8, IL-17,
IL-17A, IL17
6p12   NM_002190.2 NP_002181.1 154
IL17B Interleukin 17B UNQ516/PRO1031, IL-17B,
IL-20,
MGC138900,
MGC138901,
ZCYTO7
5q33.1   NM_014443.2 NP_055258.1 179
IL17C Interleukin 17C UNQ561/PRO1122, CX2,
IL-17C, IL-21,
MGC126884,
MGC138401
16q24   NM_013278.3 NP_037410.1 196
IL17D Interleukin 17D IL-22, IL-27,
IL-17D, FLJ30846
13q11   NM_138284.1 NP_612141.1 201
IL17F Interleukin 17F IL-17F, ML-1, ML1 6p12   NM_052872.3 NP_443104.1 162
IL18 Interleukin 18 IGIF, IL1F4, IL-18,
IL-1g, MGC12320
11q22.2-q22.3   NM_001562.2 NP_001553.1 192
IL19 Interleukin 19 RP11-262N9.2,
IL-10C, MDA1,
NG.1, ZMDA1
1q32.2 Isoform 1 NM_153758.1 NP_715639.1 214
     Isoform 2 NM_013371.2 NP_037503.2 177
IL20 Interleukin 20 UNQ852/PRO1801,
IL-20,
IL10D,
MGC96907,
ZCYTO10
1q32   NM_018724.3 NP_061194.2 175
IL21 Interleukin 21 Za11, IL-21 4q26-q27   NM_021803.2 NP_068575.1 161
IL22 Interleukin 22 UNQ3099/PRO10096,
IL-21, IL-22,
IL-D110,
IL-TIF, IL21,
ILTIF ,
MGC79382,
MGC79384,
TIFIL-23,
TIFa, zcyto18
12q15   NM_020525.4 NP_065386.1 178
IL23A Interleukin 23A UNQ2498/PRO5798, IL23,
IL-23A, IL23P19,
MGC79388,
P19, SGRF
12q13.13   NM_016584.2 NP_001717165.2 205
IL24 Interleukin 24 C49A, FISP, IL10B,
MDA7, MOB5,
ST16
1q32 Isoform 1 NM_006850.2 NP_006841.1 205
     Isoform 3 NM_001185156.1 NP_001172085.1 207
     Isoform 4 NM_001185157.1 NP_001172086.1 154
     Isoform 5 NM_001185158.1 NP_001172087.1 63
IL25 Interleukin 25 UNQ3120/PRO10272, IL17E 14q11.2 Isoform 1 NM_022789.3 NP_073626.1 176
     Isoform 2 NM_172314.1 NP_758525.1 161
IL26 Interleukin 26 AK155, IL-26 12q15   NM_018402.1 NP_060872.1 170
IL27A Interleukin 27 IL-27, IL-27A,
IL27p28,
IL30, MGC71873,
p28
16p11   NM_145659.3 NP_663634.2 242
IL28A Interleukin 28A IFNL2, IL-28A 19q13.13   NM_172138.1 NP_742150.1 199
IL28B Interleukin 28B IFNL3, IL-28B,
IL28C
19q13.13   NM_172139.2 NP_742151.2 195
IL29 Interleukin 29 IFNL1, IL-29 19q13.13   NM_172140.1 NP_742152.1 200
IL31 Interleukin 31 IL-31 12q24.31   NM_001014336.1 NP_001014358.1 164
IL32 Interleukin 32 IL-32alpha,
IL-32beta,
IL-32delta,
IL-32gamma, NK4,
TAIF, TAIFa, TAIFb,
TAIFc, TAIFd
16p13.3 Isoform a NM_001012633.1 NP_001012651.1 131
     Isoform b NM_001012631.1 NP_001012649.1 188
      NM_001012632.1 NP_001012650.1  
      NM_001012718.1 NP_001012736.1  
      NM_004221.4 NP_004212.4  
     Isoform c NM_001012634.1 NP_001012652.1 168
      NM_001012635.1 NP_001012653.1  
     Isoform d NM_001012636.1 NP_001012654.1 179
IL33 Interleukin 33 IL1F11, C9orf26,
DKFZp586H0523,
DVS27, NF-HEV ,
NFEHEV ,
RP11-575C20.2
9p24.1   NM_033439.2 NP_254274.1 270
IL34 Interleukin 34 C16orf77, IL-34,
MGC34647
16q22.1   NM_001172772.1 NP_001166243.1 242
CNTF Ciliary neurotrophic factor HCNTF 11q12.2   NM_000614.3 NP_000605.1 200
CTF1 Cardiotrophin 1 CT1, CT-1 16p11.2 Isoform 1 NM_001330.3 NP_001321.1 201
     Isoform 2 NM_001142544.1 NP_001136016.1 200
CLCF1 Cardiotrophin-like cytokine factor 1 CLC, NR6, BSF3,
NNT1, BSF-3,
CISS2, NNT-1
11q13.3 Isoform 1 NM_013246.2 NP_037378.1 225
     Isoform 2 NM_001166212.1 NP_001159684.1 215
CSF1 Colony-stimulating
factor 1
MCSF, MGC31930 1p21-p13 Isoform 1 NM_000757.4 NP_000748.3 554
     Isoform 2 NM_172210.2 NP_757349.1 438
CSF2 Colony-stimulating
factor 2
GMCSF ,
MGC131935,
MGC138897,
GM-CSF
5q31.1   NM_000758.2 NP_000749.2 144
CSF3 Colony-stimulating factor 3 GCSF, CSF3OS,
C17orf33,
MGC45931
17q11.2-q12 Isoform a NM_000759.3 NP_000750.1 207
     Isoform b NM_172219.2 NP_757373.1 204
     Isoform c NM_172220.2 NP_757374.2 171
     Isoform d NM_001178147.1 NP_001171618.1 168
LIF Leukaemia inhibitory factor CDF, DIA, HILDA 22q12.2   NM_002309.3 NP_002300.1 202
OSM Oncostatin M MGC20461 22q12.2   NM_020530.3 NP_065391.1 252
TSLP Thymic stromal lymphopoietin TSLP 5q22.1   NM_033035.4 NP_149024.1 159
  1. List of all human IL genes, as well as closely related cytokines, with full gene name, aliases, chromosomal location, isoforms, National Center for Biotechnology Information (NCBI) RefSeq mRNA accession number, NCBI RefSeq protein accession number and total amino acid number (AA#)