Figure 3

RGD's genome tools are designed to facilitate navigation and data analysis. From a genome-wide view in the GViewer, researchers can zoom in to a particular area, then view that area in the Rat GBrowse genome browser for a more complete view of the features located there. From there, navigate to the human GBrowse to determine how the features in the syntenic region of the human genome compare. Or a researcher might begin with a QTL in the human GBrowse and follow the link to the rat GBrowse to ascertain whether there are any known rat QTLs in the syntenic region. From there, researchers can move to the rat SNPlotyper to query which SNPs in that region are polymorphic between two or more rat strains. The resulting list of SNPs can be entered into the RatMine tool to view the genes associated with those SNPs and determine what functions, diseases, phenotypes or pathways may be overrepresented among those genes.