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Table 2 Association between European admixture and phenotypes (standardised parameter estimate and p-value shown, respectively)

From: Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children

 

Entire sample

Hispanic Americans

African Americans

European Americans

Total fat

0.13 (p = 0.037*)

-0.12 (p = 0.40)

0.17 (p = 0.090)

0.02 (p = 0.80)

SI

0.34 (p < 0.0001*)

0.25 (p = 0.031*)

-0.01 (p = 0.93)

0.13 (p = 0.18)

AIRg

-0.28 (p < 0.0001*)

-0.23 (p = 0.038*)

-0.13 (p = 0.19)

-0.09 (p = 0.37)

FI

-0.20 (p = 0.0013*)

-0.27 (p = 0.045*)

-0.07 (p = 0.45)

-0.02 (p = 0.79)

HOMA-IR

-0.16 (p = 0.0095*)

-0.26 (p = 0.064)

-0.11 (p = 0.25)

-0.005 (p = 0.96)

  1. Covariates: age, sex, Tanner stage, SES, total fat, height (for AIR, we also controlled for SI).
  2. *p < 0.05.
  3. SI, insulin sensitivity; AIRg, acute insulin response to glucose; FI, fasting insulin; HOMA-IR, Homeostasis model assessment of insulin resistance.
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Human Genomics

ISSN: 1479-7364