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Table 1 Significantly different TagSNPs in the Xhosa and CMA populations

From: Analysis of pharmacogenetic traits in two distinct South African populations

Gene

rsID

Minor allele

Xhosa MAF

CMA MAF

Bonferroni pvalue

ABCB1

rs13233308

T

0.01

0.18

1.77E-05

CYP3A5

rs4646450

C

0.03

0.17

0.004

UGT1A1

rs7572563

G

0.14

0.32

0.011

CYP2C18

rs2860840

T

0

0.09

0.015

CYP3A4

rs2738258

G

0.35

0.17

0.026

CYP2A7P1

rs11666982

G

0.22

0.43

0.028

UGT1A1

rs4148329

T

0.21

0.41

0.045

ABCB1

rs1202184

A

0.1

0.26

0.046

  1. CMA, Cape Mixed Ancestry; MAF, minor allele frequency; rsID, ref SNP number ID.