Table 1 Available datasets in e-PKGene
From: e-PKGene: A knowledge-based research tool for analysing the impact of genetics on drug exposure
Curated facts from publications |
|---|
   Natural language descriptions/comments |
   Quantitative data (eg AUC, Cmax, half-life, Tmax) |
   Variant details |
   Genotype details |
   Phenotype details |
   Population details (eg ethnicity, gender) |
   External links to PubMed |
Design and methods details |
   Design and drug administration |
   Genotyping method |
   Phenotyping method |
   Alleles and genes tested |
   Pharmacokinetics measurements |
   Pharmacodynamics measurements/protocol |
   Side effects |
Drug information |
   Pharmacology and interactions |
   Metabolising enzymes and transporters involved |
   Classification (therapeutic uses, therapeutic range) |
   PubChem record, CAS number |
Genetic information |
   Gene (common name, synonyms) |
   Genetic variations (DNA sequence variations [SNP], rs numbers) |
   AUC, area under the curve; Cmax, maximum (peak) observed drug concentration; Tmax, time to reach maximum concentration following drug administration; CAS, Chemical Abstracts Service |