Table 1 Prevalence of neoplasms in a cohort ( N = 149 with known NF1 mutation) of clinically well-characterized NF1 patients

CNS gliomas (excluding optic gliomas)

12

8

Malignant peripheral nerve sheath tumor

8

5.5

Rhabdomyosarcoma (prostate)

1

0.7

Medullary thyroid carcinoma

2

1.3

Gastrointestinal stromal tumors

2

1.3

Multiple internal neurofibromas

3

2

Phaechromocytoma

3(1B/L)

2

Colorectal carcinoma at 71 years

1

0.7

Breast cancer - ductal type at 34 and 40 years

2

1.3

Glomus tumor

2

1.3

Xanthogranuloma

2

1.3

Lipoma

4

2.7

Juvenile myelomonocytic leukemia

0

0