Skip to main content

Table 2 Priority cancer chemopreventive agents

From: Mitochondrial and nuclear genomics and the emergence of personalized medicine

Class of agent Chemical/brand name Preventive targets
Selective estrogen receptor modulators and other hormonal agents Tamoxifen Breast
Arzoxifene Breast
Acolbifene Breast
Raxoxifene/Evista® Breast
Finasteride Prostate
Nonsteroidal anti- inflammatory drugs Celecoxib/Celebrex® Colon, breast, prostate, bladder
Sulindac/Clinoril® Esophagus, skin
Minerals and micronutrients Calcium compounds Colon
Glucocorticoids Budesonide Lung
Retinoids All-trans-retinoic acid tretinoin/Retin-A® Cervix, esophagus, larynx, lung,
  9-cis-Retinoic acid alitretinoin/Panretin® Nasopharynx, oral cavity, ovary
  13-cis-Retinoic acid isotreninoin/Accutane®  
  4-Hydroxyretinamide, (4-HPR) fenretinide  
  1. Adapted from [21, 22].