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Table 4 Demographics and clinical data of the studied patients

From: New susceptibility locus for obesity and dyslipidaemia on chromosome 3q22.3

 

Controls

Cases

All

Male

Female

All

Male

Female

Demographics

      

 OBS

2,586

1,886(0.73)

700(0.27)

1,764

967(0.55)

797(0.45)

 Agea

53.8 ± 0.5

56.4 ± 0.3

51.1 ± 0.7

55.6 ± 0.4

55.5 ± 0.4

55.7 ± 0.4

 BMIa

25.3 ± 0.1

25.3 ± 0.1

25.2 ± 0.1

34.9 ± 0.2

33.8 ± 0.1

35.9 ± 0.2

 CAD

2,221

1,189(0.54)

1,032(0.46)

2,429

1,860(0.66)

569(0.34)

 MI

1,590

787(0.49)

803(0.51)

3,060

2,262(0.74)

798(0.26)

 FH

3,730

2,449(0.66)

1,283(0.34)

920

602(0.65)

318(0.35)

 T2DM

2,090

1,336(0.64)

754(0.36)

2,560

1,713(0.55)

847(0.45)

 HTN

1,109

735(0.66)

374(0.34)

3,541

2,314(0.65)

1,227(0.35)

 lHDLC

2,516

1,487(0.59)

1,029(0.41)

1,935

1,487(0.77)

448(0.23)

 hLDLC

3,696

2,449(0.75)

1,029(0.25)

860

634(0.74)

226(0.26)

 hChol

2,744

1,801(0.66)

943(0.34)

1,686

1,117(0.66)

569(0.34)

 hTG

3,168

2,028(0.64)

1,140(0.36)

1,166

829(0.71)

337(0.29)

 Smokers

2,791

1,314(0.47)

1,477(0.53)

1,771

1,694(0.96)

77(0.04)

Clinical characteristics (relative to coronary artery disease)

      

 Age

50.6 ± 0.4

51.2 ± 0.5

49.8 ± 0.5

60.3 ± 0.2

59.8 ± 0.3

61.8 ± 0.54

 BMI

29.0 ± 0.2

27.97 ± 0.2

30.3 ± 0.3

28.9 ± 0.1

28.3 ± 0.1

31.0 ± 0.3

 Total chol

4.51 ± 0.02

4.42 ± 0.03

4.62 ± 0.03

4.48 ± 0.02

4.43 ± 0.03

4.66 ± 0.05

 HDL-chol

1.26 ± 0.01

1.18 ± 0.03

1.33 ± 0.01

1.15 ± 0.01

1.15 ± 0.01

1.25 ± 0.02

 LDL-chol

2.76 ± 0.02

2.73 ± 0.03

2.80 ± 0.03

2.71 ± 0.02

2.68 ± 0.02

2.84 ± 0.06

 TG

1.52 ± 0.02

1.60 ± 0.03

1.44 ± 0.03

1.78 ± 0.02

1.78 ± 0.03

1.78 ± 0.05

 FG

6.87 ± 0.16

6.80 ± 0.23

6.92 ± 0.22

9.45 ± 0.31

9.27 ± 0.37

9.88 ± 0.56

 BP

120/83

119/81

121/82

128/84

130/85

127/83

  1. The numbers in brackets give the fraction of the total (all) values of the group. BMI body mass index, CAD coronary artery disease, FH family history of CAD, MI myocardial infarction, FG fasting glucose, T2DM type 2 diabetes mellitus, lHDLC low high-density lipoprotein-cholesterol, hLDLC high low-density lipoprotein-cholesterol, hTG hypertriglyceridaemia, hChol hypercholesterolaemia, HTN hypertension. aValues relative to obesity as the case group.