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Figure 3 | Human Genomics

Figure 3

From: Development of a cost-effective high-throughput process of microsatellite analysis involving miniaturized multiplexed PCR amplification and automated allele identification

Figure 3

Microsatellite profiles of group I markers of family members in lineage determination. The x-axis represents the DNA fragment size in base pairs, and the y-axis represents the fluorescence units. Relationships among family members were predicted based on the patterns of inheritance of microsatellite alleles. Child 1 and 2 are monozygotic twins. (A) Microsatellite profile of child 1. Automated identification accurately called inherited microsatellite alleles of dinucleotide markers, which can be traced back to the microsatellite profiles of parent 1 and parent 2. (B) Microsatellite profile of parent 1. Alleles have been automatically called with optimized methods. (C) Microsatellite profile of parent 2. Alleles have been automatically called with optimized methods. (D) Microsatellite profile of child 2. Automated identification accurately called inherited microsatellite alleles of dinucleotide markers, which can be traced back to the microsatellite profiles of parent 1 and parent 2.

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