Gene symbol | Fold change | pvalue | Function | Activity | Role in cancer |
---|---|---|---|---|---|
ANLN | 3.55 | 0.0053 | Â | Actin-binding protein | Overexpressed in pancreatic carcinoma |
NAV3 | 1.65 | 0.0099 | G | Neuron growth, regeneration | Neural tumorigenesis |
ZNF718 | 1.61 | 0.0064 | Â | Zinc finger protein | Associated with prostate cancer |
PSCD3 | 1.59 | 0.0035 | T | Protein sorting and membrane trafficking | Â |
C180rf54 | 1.57 | 0.0047 | Â | Â | Overexpressed in multiple cancers |
XPO1 | 1.56 | 0.0079 | T/K | Nuclear protein transport export | Â |
C10rf79 | 1.56 | 0.0065 | Â | Â | Â |
GMNN | 1.55 | 0.0032 | G | Proliferation marker | Correlated with poorer clinical outcome |
WHSC1 | 1.51 | 0.006 | Â | Regulation of Wnt pathway | Expression increases with ascending glioma proliferation activity |
EPHA2 | 1.51 | 0.0073 | K | Tyrosine Kinase | Overexpressed in many types of cancer |
SNF1LK2 | -2.03 | 0.0055 | K | Serine/Threonine kinase | Correlated with ovarian cancer poor survival |
NGFRAP1L1 (BEX5) | -1.8 | 0.0009 | G | Nerve growth factor receptor-associated | May be a tumor suppressor in VS |
ELL2 | -1.8 | 0.0031 | Â | Suppress canonical Wnt signaling | ELL translocations in malignancies. |
SYTL3 | -1.79 | 0.0053 | T | Vesicular trafficking | Â |
KCNK17 | -1.76 | 0.006 | Â | Potassium channel | Expressed abnormally in many cancer types |
IGLV1-44 | -1.68 | 0.0057 | Â | Â | Â |
PID1 | -1.62 | 0.0084 | Â | Glucose transport inhibitor | Â |
RGN | -1.59 | 0.0052 | Â | Suppresses cell proliferation | Lost in breast and prostate cancer |
PTPN1 | -1.57 | 0.0076 | K/G | Cell growth | Â |
ZNF331 | -1.53 | 0.0074 | D | Induces apoptosis | Â |
RNF19A | -1.52 | 0.0025 | D | Neuronal cell death | Â |