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Table 3 The number of genes selected based on (a) bivariate mixture model, (b) conventional one-species approach

From: Mixture models for gene expression experiments with two species

 

Categories (1,2,3,4,5,6)

Categories (1,2,3,4,7,8)

 

Mixture

Avg FDR I

Human only

Mixture

Avg FDR II

Animal only

sim1

132

0.034

100(0.070)

129

0.029

96(0.063)

sim2

224

0.003

145(0.021)

223

0.012

188(0.016)

sim3

113

0.246

85(0.318)

135

0.048

109(0.073)

sim4

166

0.050

115(0.043)

222

0.012

188(0.016)

sim5

132

0.028

98(0.041)

234

0.004

238(0.012)

sim6

227

0.011

194(0.021)

289

0.003

289(0.007)

sim7

112

0.235

78(0.282)

241

0.011

246(0.020)

sim8

167

0.048

124(0.065)

288

0.002

288(0.007)

Tukey’s HSD

30.908

0.021

 

52.958

0.016

 

sim9

92

0.126

81(0.296)

88

0.129

75(0.307)

sim10

118

0.033

104(0.048)

118

0.036

99(0.061)

sim11

141

0.470

109(0.670)

80

0.128

70(0.214)

sim12

103

0.116

68(0.118)

118

0.049

102(0.088)

sim13

84

0.140

67(0.169)

180

0.349

167(0.407)

sim14

120

0.023

88(0.023)

152

0.022

151(0.101)

sim15

119

0.480

99(0.636)

168

0.358

157(0.369)

sim16

96

0.093

57(0.105)

147

0.020

148(0.061)

Tukey’s HSD

3.947

0.011

 

2.337

0.004

 
  1. Under simulation studies case I and case II. Numbers in parentheses are the observed FDRs. Averaged over the 500 simulated datasets. Tukey’s HSD for an α level of 0.05 is included beneath each set of eight simulation cases.