Skip to main content
Figure 6 | Human Genomics

Figure 6

From: A gene-specific non-enhancer sequence is critical for expression from the promoter of the small heat shock protein gene αB-crystallin

Figure 6

GPS is essential for the cryab promoter activity in transgenic mice. Relative tGFP expression was assayed in transgenic mice with GPS (+GPS), without GPS (ΔGPS) and wild type non-transgenic mice (WT). RT-qPCR analysis of tGFP expression in 11 mouse tissues is shown. Two transgenic lines and two WTs were analyzed, but no tissues were pooled. No tGFP is seen in ΔGPS and WT animals. Le lens, Re retina, Eg eye globe without the lens and retina, Li liver, He heart, Lu lung, Sp spleen, Ki kidney, Si small intestine, Mu muscle, Br brain. The inset is a screen shot of the raw data from the 480 cycler (Roche).The dotted vertical line separates the + GPS samples from the ΔGPS and WT samples.

Back to article page

Human Genomics

ISSN: 1479-7364