Table 3 Scoring multiple mutations in β MHC and MyBP-C genes
From: Predicting the combined effect of multiple genetic variants
Gene | Mutation1 | Score1 | Mutation2 | Score2 | Set score |
|---|---|---|---|---|---|
βMHC | Val39Met | 1.7 | Arg723Cys | 3.4 | 5.0 |
βMHC | Pro211Leu | 2.4 | Arg663HIs | 2.2 | 4.5 |
βMHC | Met349Thr | 2.2 | Arg719Trp | 3.1 | 5.3 |
βMHC | Arg663His | 2.2 | Val763Met | 2.3 | 4.4 |
βMHC | Arg719Gln | 1.7 | Thr1513Ser | 0.0 | 1.6 |
βMHC | Asp906Gly | 2.7 | Leu908Val | 2.0 | 4.6 |
MyBP-C | Gly5Arg | 1.7 | Arg502Trp | 4.9 | 5.7 |
MyBP-C | Arg502Trp | 3.9 | Ser858Asn | 2.4 | 6.4 |
MyBP-C | Alu542Gln | 2.2 | Ala851Val | 2.2 | 4.4 |
MyBP-C | Asp745Aly | 3.9 | Pro873His | 4.0 | 7.9 |
MyBP-C | Arg810His | 2.9 | Arg820Gln | 2.6 | 5.5 |