Table 1 Human FANC genes
Gene symbol (NCBI gene ID) | Gene name | FANC symbol | Gene symbol synonyms | Chromosomal location | Ref seq RNA | Ref seq protein | Protein size (aa) |
|---|---|---|---|---|---|---|---|
FANCA (2175) | Fanconi anemia complementation group A | FANCA | FA, FA-H, FA1, FAA, FACA, FAH, FANCH | 16q24.3 | NM_000135.2 | NP_000126.2 | 1,455 |
FANCB (2187) | Fanconi anemia complementation group B | FANCB | FA2, FAAP90, FAAP95, FAB, FACB | Xp22.31 | NM_001018113.1 | NP_001018123.1 | 859 |
FANCC (2176) | Fanconi anemia complementation group C | FANCC | RP11-80I15.2, FA3, FAC, FACC | 9q22.3 | NM_000136.2 | NP_000127.2 | 558 |
BRCA2 (675) | Breast cancer 2 | FANCD1 | RP11-298P3.4, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, GLM3, PNCA2, XRCC11 | 13q12.13 | NM_000059.3 | NP_000050.2 | 3,418 |
FANCD2 (2177) | Fanconi anemia complementation group D2 | FANCD2 | FA-D2, FA4, FACD, FAD, FAD2, FANCD | 3p25.3 | NM_001018115.1 | NP_001018125.1 | 1,451 |
FANCE (2178) | Fanconi anemia complementation group E | FANCE | FACE, FAE | 6p21.22 | NM_021922.2 | NP_068741.1 | 536 |
FANCF (2188) | Fanconi anemia complementation group F | FANCF | FAF | 11p15 | NM_022725.3 | NP_073562.1 | 374 |
FANCG (2189) | Fanconi anemia complementation group G | FANCG | FAG, XRCC9 | 9p13 | NM_004629.1 | NP_004620.1 | 622 |
FANCI (55215) | Fanconi anemia complementation group I | FANCI | KIAA1794 | 15q26.1 | NM_001113378. | NP_001106849.1 | 1,328 |
BRIP1 (83990) | BRCA1 interacting protein C-terminal helicase 1 | FANCJ | BACH1, OF | 17q23.2 | NM_032043.2 | NP_114432.2 | 1,249 |
FANCL (55120) | Fanconi anemia complementation group L | FANCL | FAAP43, PHF9, POG | 2p16.1 | NM_001114636.1 | NP_001108108.1 | 380 |
FANCM (57697) | Fanconi anemia complementation group M | FANCM | FAAP250, KIAA1596 | 14q21.3 | NM_020937.2 | NP_065988.1 | 2,048 |
PALB2 (79728) | Partner and localizer of BRCA2 | FANCN | PNCA3 | 16p12 | NM_024675.3 | NP_078951.2 | 1,186 |
RAD51C (5889) | RAD51 paralog C | FANCO | ROVCA3, R51H3, RAD51L2 | 17q23 | NM_002876.3 | NP_002867.1 | 376 |
SLX4 (84464) | SLX4 structure-specific endonuclease subunit | FANCP | BTBD12, MUS312 | 16p13.3 | NM_032444.2 | NP_115820.2 | 1,834 |
ERCC4 (2072) | Excision repair cross-complementation group 4 | FANCQ | RAD1, XPF, ERCC11 | 16p13.12 | NM_005236.2 | NP_005227.1 | 916 |
RAD51 (5888) | RAD51 recombinase | FANCR | BRCC5, HRAD51, HsRad51, HsT16930, MRMV2A, RECA | 15q15.1 | NM_001164269.1 | NP_001157741.1 | 340 |
BRCA1 (672) | Breast cancer 1 | FANCS | BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53 | 17q21.31 | NM_007294.3 | NP_009225.1 | 1863 |
UBE2T (29089) | Ubiquitin- conjugating enzyme E2T | FANCT | HSPC150 | 1q32.1 | NM_014176.3 | NP_054895.1 | 197 |