Fig. 1

Navigating through the gene family resource. Within the figure, ‘Cholinergic receptors’ was entered in to the search field and three results were returned. Clicking on the first result will navigate to the family ‘Cholinergic receptors’ (arrow a) whilst the second result navigates to the family ‘Cholinergic receptors, muscarinic’ (arrow b), a subset of ‘Cholinergic receptors’. It is possible to move through the hierarchy levels by clicking on the ‘A subset of’ link within the subset family (arrow c), by hovering the cursor over a family of interest within the ‘Gene family hierarchy map’ and clicking ‘View gene family’ within the tooltip (arrow d), or by clicking on a ‘Family contains the following subsets’ link (arrow e). Within a gene family report, it is possible to view the gene symbol report for each gene specified in the family by clicking on the approved symbol (arrow f). The resulting symbol report will have a ‘GENE FAMILY’ field within the top section of the page. It is possible for a gene to be a direct member of several families and if this is the case, they will all be listed within this field. Since the gene CHRM4 is a direct member of ‘Cholinergic receptors, muscarinic’, this family is listed in the CHRM4 symbol report and links back to the family (arrow g)