Fig. 5
From: Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD
Relative transcriptogram for C-ADPKD/NK. The x-axis indicates the relative position in the ordered list of 9684 genes. Upper panel We present the relative transcriptograms as means ± s.e.m. with C-ADPKD (red line ± pink region) and NK (black line ± gray region) given relative to NK. Center panel (shaded gray): P value from a two-tailed Weyl’s t test for each point of the transcriptogram. Horizontal lines mark P = 0.05 and P = 0.01. We label the location in the ordered list of Pkd1 and Pkd2, the causative genes for ADPKD. Lower panel Term enrichment for transcriptogram regions with gene expression significantly different from normal. A term enrichment value of 1 on the y-axis indicates that all genes in an interval of radius r = 30 participate in a given GO term or KEGG pathway