Fig. 8
From: Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD
Genetic information processing is altered in ADPKD. NC-ADPKD cells have higher-than-normal expression and C-ADPKD cells have lower-than-normal expression of genes from all ‘Genetic information processing’ gene sets except the KEGG ribosome gene set. We present data as mean ± s.e.m., **P < 0.01, *P < 0.05 (black asterisk is in comparison to NK, gray asterisk is in comparison to NC-ADPKD). Genetic Information Processing Gene Sets: (1) KEGG_DNA_REPLICATION, (2) KEGG_BASE_EXCISION_REPAIR, (3) KEGG_NUCLEOTIDE_EXCISION_REPAIR, (4) KEGG_MISMATCH_REPAIR, (5) KEGG_HOMOLOGOUS_RECOMBINATION, (6) DNA_REPLICATION, (7) DNA_REPAIR, (8) KEGG_RNA_POLYMERASE, (9) KEGG_BASAL_TRANSCRIPTION_FACTORS, (10) KEGG_SPLICEOSOME, (11) TRANSCRIPTION, (12) REGULATION_OF_TRANSCRIPTION, (13) TRANSCRIPTION_DNA_DEPENDENT, (14) REGULATION_OF_TRANSCRIPTION_DNA_DEPENDENT, (15) TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER, (16) KEGG_RIBOSOME, (17) RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY, (18) PROTEIN_RNA_COMPLEX_ASSEMBLY, (19) MRNA_PROCESSING_GO_0006397, (20) RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS