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Table 3 Down-regulated genes of the severe MPP group comparing to the mild MPP group

From: Transcriptome analysis of bronchoalveolar lavage fluid from children with severe Mycoplasma pneumoniae pneumonia reveals novel gene expression and immunodeficiency

Gene ID Associated gene name log2foldchange padj Description
ENSG00000163687 DNASE1L3 −4.90655 0.002613 Deoxyribonuclease I-like 3
ENSG00000166428 PLD4 −4.12788 0.005539 Phospholipase D family member 4
ENSG00000269404 SPIB −3.62528 0.008687 Spi-B transcription factor (Spi-1/PU.1 related)
ENSG00000081059 TCF7 −2.83313 0.021184 Transcription factor 7 (T cell specific, HMG-box)
ENSG00000156738 MS4A1 −3.80125 0.029750 Membrane-spanning 4-domains, subfamily A, member 1
ENSG00000159958 TNFRSF13C −3.59110 0.029750 Tumor necrosis factor receptor superfamily member 13C
ENSG00000233308 OSTN-AS1 −7.65241 0.029750 OSTN antisense RNA 1
ENSG00000253364 RP11-731F5.2 −5.82530 0.029750
ENSG00000111796 KLRB1 −3.80851 0.032804 Killer cell lectin-like receptor subfamily B, member 1
ENSG00000164485 IL22RA2 −7.13138 0.032804 Interleukin 22 receptor subunit alpha 2
ENSG00000253998 IGKV2-29 −6.19209 0.032804 Immunoglobulin kappa variable 2–29 (gene/pseudogene)
ENSG00000168542 COL3A1 −6.89272 0.036862 Collagen, type III, alpha 1
ENSG00000170801 HTRA3 −4.50354 0.036862 HtrA serine peptidase 3
Novel00339 −3.48127 0.041780
ENSG00000142173 COL6A2 −4.69524 0.042554 Collagen, type VI, alpha 2
ENSG00000100721 TCL1A −4.49274 0.044977 T cell leukemia/lymphoma 1A
ENSG00000142156 COL6A1 −4.52065 0.044977 Collagen, type VI, alpha 1
ENSG00000111732 AICDA −3.71025 0.055876 Activation-induced cytidine deaminase
ENSG00000164692 COL1A2 −3.75418 0.059895 Collagen, type I, alpha 2
ENSG00000105369 CD79A −3.63713 0.069048 CD79a molecule
ENSG00000276775 IGHV4-4 −5.43537 0.069048 Immunoglobulin heavy variable 4-4
ENSG00000080573 COL5A3 −3.37399 0.090838 Collagen, type V, alpha 3
ENSG00000163518 FCRL4 −4.51056 0.090838 Fc receptor-like 4
ENSG00000196092 PAX5 −2.93710 0.093937 Paired box 5
ENSG00000177455 CD19 −3.44060 0.110361 CD19 molecule
ENSG00000136573 BLK −3.67317 0.128424 BLK proto-oncogene, Src family tyrosine kinase
ENSG00000203963 C1orf141 −6.39692 0.130273 Chromosome 1 open reading frame 141
ENSG00000258752 RP11-356K23.1 −4.39265 0.130273
ENSG00000167483 FAM129C −2.78386 0.148367 Family with sequence similarity 129 member C
ENSG00000215218 UBE2QL1 −3.91473 0.149275 Ubiquitin conjugating enzyme E2Q family-like 1
ENSG00000050165 DKK3 −3.95056 0.186854 Dickkopf WNT signaling pathway inhibitor 3
ENSG00000132185 FCRLA −3.11003 0.186854 Fc receptor-like A
ENSG00000183853 KIRREL −5.37583 0.186854 Kin of IRRE like (drosophila)
ENSG00000117215 PLA2G2D −2.60098 0.191201 Phospholipase A2 group IID
  1. log 2 foldchange log2 (severe MPP/mild MPP), padj adjusted p value, Novel novel gene