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Table 2 Genotyping data of sALS patients and their healthy counterparts

From: Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients

Population groups Genotype frequency (%)
FTO rs2892469 FTO rs1861869 FTO rs17217144 FTO rs7186521 TBC1D1 rs6850200
CC TT CT p value CC GG CG p value CC TT CT p value AA GG AG p value AA CC CA p value
Second patient cohort Greek healthy individuals 26 36 38 0.005 21 41 38 0.003 0 0 100 PA = 1.55e−12  PB = 7.78e−13 0 0 100 1.0 18 45 38 0.017
Greek sALS patients 17 22 61 17 22 61 22 13 65 0 0 100 9 35 57
Third patient cohort Greek healthy individuals 26 36 38 0.033 21 41 38 PA = 0.072
PB = 0.071
6 2 92 0.002 0 0 100 5.13e−39 14 43 43 0.723
Greek sALS patients 21 23 56 17 29 54 22 2 76 18 65 18 11 42 48
Sardinian healthy individuals 38 25 38 0.63 36 31 33 0.61 24 36 40 0.67 35 22 42 0.64 20 41 39 0.53
Sardinian sALS patients 31 28 41 29 34 37 27 30 43 29 25 46 15 39 46
Turkish healthy individuals 26 26 49 0.62 0 100 0 0.49 26 26 49 0.62 26 26 49 0.09 18 45 38 0.57
Turkish sALS patients 24 21 55 0 99 1 26 20 54 21 26 53 13 44 43